Slow walking speed in midlife linked with faster aging
13 October, 2019
New research finds that people who tend to walk more slowly at the age of 45 present with signs of premature accelerated aging, both physically and cognitively.
Walking speed may be a powerful predictor of lifespan and health.
A recent study, reported on by Medical News Today, found that the faster a person walks, the longer they may live, with older adults benefitting the most from a brisk pace.
Medical professionals have long used gait speed as a marker of health and fitness among older adults, but the new research asks a slightly different question: Does a slow gait speed in midlife indicate and predict accelerated aging?
Line J. H. Rasmussen, Ph.D., a researcher in the department of psychology and neuroscience at Duke University, in Durham, NC, and colleagues set out to answer this question by examining data from 904 study participants.
Rasmussen and the team published their findings in the journal JAMA Network Open.
Cognition, overall health, and gait speed
The researchers assessed participants' data from the Dunedin Multidisciplinary Health and Development Study, a longitudinal cohort study of people living in Dunedin, New Zealand.
The participants have undergone periodic testing for most of their lives. The researchers have been tracking the participants' general health and behavior, with assessments beginning when participants were 3 years old.
At the time, a pediatric neurologist used standard intelligence tests to assess the children's neurocognitive performance, including their receptive language, motor skills, and emotional and behavioral regulation.
The researchers had access to data such as IQ scores — including processing speed, working memory, perceptual reasoning, and verbal comprehension.
The researchers evaluated the now-adult participants' walking speeds under three conditions: usual gait speed, dual task gait speed — wherein the participants had to walk as usual while reciting the alphabet — and maximum gait speed.
The team also evaluated the physical function of the adults by asking them to self-report in a survey and complete a series of physical tasks that tested their grip strength, balance, and hand-eye coordination, among other factors.
To assess accelerated aging, the team looked at a variety of biomarkers, including body mass index, waist-to-hip ratio, blood pressure, cardiorespiratory fitness, total cholesterol level, triglycerides level, high-density lipoprotein cholesterol level, creatinine clearance, blood urea level, C-reactive protein level, white blood cell count, and gum and teeth health.
The researchers also evaluated the adults' brain health using MRI scans.
Additionally, the scientists brought in an independent panel of 8 people who assessed the ages of the participants using standardized photos of their faces at age 45.