Just 6 hours of sleep loss increases diabetes risk
10 September, 2018
The importance of sleep is well-known. A recent study enforces this by demonstrating that sleep deprivation might increase diabetes risk — after losing just 1 night of sleep.
Sleep is undoubtedly one of physiology's most mysterious but essential functions.
We all need it, yet the exact reasons why it's so important are still being debated.
What we do know is that sleep is important for memory consolidation; it also seems to afford the brain time to clear out toxins that built up throughout the day.
A lack of sleep has a two-way relationship with psychiatric conditions: sleep disturbance can be caused by mental illness, and sleep deprivation can exacerbate, or even cause, mental illnesses.
Physically, sleep allows the body to recuperate; for instance, muscles are given time to heal and grow.
Sleep deprivation is considered to be a large-scale concern in the United States. Due to a range of factors — including excessive screen time, artificial lighting, busy lives, and hectic jobs — around 1 in 3 people in the U.S. do not get the recommended 7 hours of sleep each night.
Scientists are still unraveling this epidemic's potential consequences on health.
Lack of sleep and diabetes
Studies have already shown that people who do not get enough sleep are more likely to eat more, exercise less, and put on excess weight.
Studies have also shown an increased risk of diabetes, but exactly why diabetes might occur has not been understood.
A new study expands on our understanding of this relationship. The authors of the latest study, at Toho University Graduate School of Medicine in Japan, explain further, saying:
"It was not clear whether glucose intolerance was due to the changes in food intake or energy expenditure or to the sleep deprivation itself."
In other words, are the changes in diet and exercise related to poor sleep the reason for a rise in diabetes risk, or is something else at work? The researchers set out to understand exactly why sleep deprivation might undermine insulin sensitivity.
To do so, they used a mouse model, focusing on changes in their livers. For just 1 night, they kept half of the mice awake for 6 hours during their usual sleep time.
The scientists observed the mice carefully and, every time they appeared to be dozing off, they would gently handle or touch them. In this way, they kept them awake without causing undue stress to the animal.
To pick apart the impact of lifestyle factors, for 2 weeks before the study began, all mice were given access to unlimited high-fat food and sugar water; also, the mice had their movement restricted.
This way, the researchers could observe the effect of sleep deprivation in isolation because, whether the mice had slept or not, they were fed similar diets and could not exercise.